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In part, thisinformation has been developed using sophis-ticated mathematical modeling, and the overallcomplexity of the modeling makes straightfor-ward application of this information at the bed-side to improve aerosol delivery dif?cult. It is one of the two optional NRTIs usedby NACO for its first line triple drug ARVregimen. The best example isventilator- generated CPAP. Patients experience severe arm pain, weakness, and atrophy of muscles. This phenomenon isoften seen in the lymph nodes of the neck in response tonasal or oropharyngeal infection and in axillary and inguinalregions because ofinfection in extremities

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Functional results of orthotopic ileal neobladder withserous-lined extramural ureteral reimplantation: Experience with 450 patients. It wasproposed about 20 years ago [ 14 , 28 , 152] that mutant p53 may transactivategenes it up-regulates indirectly through interactions with transcriptionfactors that normally bind to the regulatory regions of those target genes.Various groups have shown interactions of p53 (both WT and mutant)with several transcription factors including Sp1, E2F1, Ets1, CREB,p300/CREBP, NFY-A [ 14 , 30 , 43 , 48 , 78 , 87 , 93 , 137] and others.Although in some cases evidence has been presented that indicates nucle-ation of mutant p53 on DNA by anchoring onto another transcription fac-tor, in most cases there is a lack of clear-cut evidence

It wasproposed about 20 years ago [ 14 , 28 , 152] that mutant p53 may transactivategenes it up-regulates indirectly through interactions with transcriptionfactors that normally bind to the regulatory regions of those target genes.Various groups have shown interactions of p53 (both WT and mutant)with several transcription factors including Sp1, E2F1, Ets1, CREB,p300/CREBP, NFY-A [ 14 , 30 , 43 , 48 , 78 , 87 , 93 , 137] and others.Although in some cases evidence has been presented that indicates nucle-ation of mutant p53 on DNA by anchoring onto another transcription fac-tor, in most cases there is a lack of clear-cut evidence. Bannister and Fransella 1970;Guidano 1987; Ryle 1990). 13.12 Airway pressure (cm H2O) and ?ow (mL/s)waveforms measured at the airway opening during fouroscillatory cycles (Sensormedics 3100A high-frequencyoscillatory ventilator) in a term infant with meconiumaspiration syndrome.

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