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Disclosure means that the potential sub-ject is provided with as much information as possible regarding the nature of thestudy, its risks, bene?ts, and rationale, prior to enrolment.

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Like ?-blockers, this reduces myocardialcontractility resulting in a reduction in myocardial oxygendemand.

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For example, in the areaof treatment response, sociologists have shown how gendered categories and responses revealembodied relations of affect and social conditions that underlie responses to treatment (e.g. The serum markers were measured in stored samples(from a biobank), which came from a case–control study of 75 Down’ssyndrome and 367 unaffected pregnancies, matched for maternal age,gestational age, and duration of storage of the serum sample, plus samplesfrom 970 Caucasian women with unaffected pregnancies [9]

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